Dr Po-Chi Soo

Dr. Po-Chi Soo

Research interests

Four research topics are studying by our research group.

  1. Study of biodegradable plastics.
  2. Study of the biofilm formation in Klebsiella pneumoniae.
  3. Development of methods to identify and kill pathogenic bacteria.
  4. Study of the wo component signal transduction system in bacterial Serratia marcescens.

 

 

Publications and patents

  1. Jwu-Ching Shu, Po-Chi Soo, Jung-Chi Chen, Shu-Han Hsu, Lei-Chin Chen, Chien-Yen Chen, Shih-Hsiung Liang, Leh-Miauh Buu, Chien-Cheng Chen (2013, Nov). Differential regulation and activity against oxidative stress of Dps proteins in Bacillus cereus. International Journal of Medical Microbiology, 662-673. (SCI, 24/116, MICROBIOLOGY).
  2. Soo PC, Horng YT, Chang YL, Tsai WW, Jeng WY, Lu CC, Lai HC (2013, Oct). ManA is regulated by RssAB signaling and promotes motility in Serratia marcescens. Research in microbiology. (Accepted). (SCI, 45/116,MICROBIOLOGY).
  3. Lai MJ, Soo PC, Lin NT, Hu A, Chen YJ, Chen LK, Chang KC. (2013, Aug). Identification and characterisation of the putative phage-related endolysins through full genome sequence analysis in Acinetobacter baumannii ATCC 17978.. International journal of antimicrobial agents, 42(2):141-8. (SCI, 25/116, MICROBIOLOGY).
  4. Liou ML, Soo PC, Ling SR, Kuo HY, Tang CY, Chang KC (2013, Feb). The sensor kinase BfmS mediates virulence in Acinetobacter baumannii. Journal of microbiology, immunology, and infection . (SCI, 82/116, MICROBIOLOGY).
  5. Soo PC, Tseng CC, Ling SR, Liou ML, Liu CC, Chao HJ, Lin TY, Chang KC. (2012, Dec). Rapid and sensitive detection of Acinetobacter baumannii using loop-mediated isothermal amplification. Journal of Microbiological Methods , 197-200. (SCI, 68/114, Microbiology).
  6. -T. Horng, C.-C. Chien, C.-T. Huang, Y.-H. Wei, S.-Y. Chen, J.C.-W. Lan, P.-C. Soo (2012, Dec). Biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with co-expressed propionate permease (prpP), Beta-ketothiolase B (bktB), and propionate-CoA synthase (prpE) in Escherichia coli . Biochemical Engineering Journal, 73-79. (SCI, 21/133, ENGINEERING, CHEMICAL).
  7. Soo PC, Kung CJ, Horng YT, Chang KC, Lee JJ, Peng WP. (2012, Sep). Detonation nanodiamonds for rapid detection of clinical isolates of Mycobacterium tuberculosis complex in broth culture media.. Analytical Chemistry, 84(18):7972-8.. (SCI, 3/73 , CHEMISTRY, ANALYTICAL). NSC 101-2320-B-320-002.
  8. Chih-Ching Chien & Hsiu-Hsiung Li & Po-Chi Soo & Shan-Yu Chen & Yu-Hong Wei &Wen-Ming Chen (2012, Jan). Effects of Different Substrate Composition on Biosynthesis of Polyhydroxybutyrate-co-hydroxyvalerate by Recombinant Escherichia coli. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY , 166:796-804. (SCI, 84/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY).
  9. Horng YT, Chien CC, Wei YH, Chen SY, Lan JC, Sun YM, Soo PC. (2011, May). Functional cis-expression of phaCAB genes for poly(3-hydroxybutyrate) production by Escherichia coli. . Letters in Applied Microbiology , 52(5):475-83. (SCI, 101/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY). NSC 97-2320-B-320-012-MY3.
  10. Lai MJ, Lin NT, Hu A, Soo PC, Chen LK, Chen LH, Chang KC. (2011, Apr). Antibacterial activity of Acinetobacter baumannii phage ϕAB2 endolysin (LysAB2) against both gram-positive and gram-negative bacteria. . Applied Microbiology and Biotechnology , 90(2):529-39. (SCI, 39/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY).
  11. Chih-Ching Chien, Chian-Chiao Hong, Po-Chi Soo, Yu-Hong Wei, Shan-Yu Chen, Mei-Ling Cheng, Yi-Ming Sun. (2010, Dec). Functional expression of phaCAB genes from Cupriavidus taiwanensis strain 184 in Escherichia coli for polyhydroxybutyrate production. . APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY., 162(8):2355-64. (SCI, 84/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY).
  12. Yu-Tze Horng, Kai-Chih Chang, Yen-Ni Liu, Hsin-Chih Lai, Po-Chi Soo* (2010, Jun). The RssB/RssA two-component system regulates biosynthesis of the tripyrrole antibiotic, prodigiosin, in Serratia marcescens. . International Journal of Medical Microbiology, Volume 300, Issue 5,P 304-312.. (SCI, 23/114, MICROBIOLOGY). NSC 97-2320-B-320-012-MY3.
  13. Horng YT, Chang KC, Chou TC, Yu CJ, Chien CC, Wei YH, Soo PC* (2010, Apr). Inactivation of dhaD and dhaK abolishes by-product accumulation during 1,3-propanediol production in Klebsiella pneumoniae.. Journal of Industrial Microbiology and Biotechnology, Apr. (37): 707-716 . (SCI, 58/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY). NSC 97-2320-B-320-012-MY3.
  14. Horng YT, Chang KC, Chien CC, Wei YH, Sun YM, Soo PC*. (2009, Nov). Enhanced polyhydroxybutyrate (PHB) production via the coexpressed phaCAB and vgb genes controlled by arabinose P promoter in Escherichia coli.. Lett Appl Microbiol. , [Epub ahead of print]. (SCI, 101/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY). NSC 97-2320-B-155-001-MY3.
  15. Soo PC, Horng YT, Chang KC, Wang JY, Hsueh PR, Chuang CY, Lu CC, Lai HC. (2009, Oct). A simple gold nanoparticle probes assay for identification of Mycobacterium tuberculosis and Mycobacterium tuberculosis complex from clinical specimens.. Mol Cell Probes, 23(5):240-6. (SCI, 77/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY ). NSC 97-2320-B-155-001-MY3.
  16. Po-Chi Soo, Yu-Tze Horng, Ying-Hsien Fu, Chia-Chen Lu, Hsin-Chih Lai (2008, Jul). A potential acyltransferase regulates swarming in Serratia marcescens.. Biochem Biophys Res Commun., 371(3):462-7. (SCI, 173/290, BIOCHEMISTRY & MOLECULAR BIOLOGY ). NSC 96-2320-B-155-001.
  17. Po-Chi Soo, Yu-Tze Horng, Jun-Rong Wei, Jwu-Ching Shu, Chia-Chen Lu, and Hsin-Chih Lai (2008, Apr). Regulation of swarming motility and flhDC(Sm) expression by RssAB signaling in Serratia marcescens.. Journal of Bacteriology, 190(7):2496-504. (SCI, 29/114, MICROBIOLOGY). NSC 96-2320-B-155-001.
  18. Shang-Chen Hsieh, Chia-Chen Lu,Yu-Tze Horng, Po-Chi Soo, Yung-Lin Chang, Yu-Huan Tsai, Chuan-Sheng Lin, Hsin-Chih Lai (2007, Oct). The bacterial metabolite 2,3-butanediol ameliorates endotoxin-induced acute lung injury in rats.. Microbes and Infection, 9(12-13):1402-9.. (SCI, 41/114, MICROBIOLOGY ).
  19. Po-Chi Soo, Yu-Tze Horng, Meng-Jiun Lai, Jun-Rong Wei, Shang-Chen Hsieh,Yung-Lin Chang, Yu-Huan Tsai, and Hsin-Chih Lai (2007, Jan). Pirin regulates pyruvate catabolism through interaction with the pyruvate dehydrogenase E1 subunit and modulating pyruvate dehydrogenase activity. Journal of Bacteriology, 189(1) P.109-P.118. (SCI, 29/114, MICROBIOLOGY).
  20. Jun-Rong Wei, Po-Chi Soo, Yu-Tze Horng, Shang-Chen Hsieh, Yu-Huan Tsai,Simon Swift, Helen Withers, Paul Williams, Hsin-Chih Lai (2006, Sep). Regulatory roles of spnT, a novel gene located within transposon TnTIR.. Biochem Biophys Res Commun., 348(3):1038-46. (SCI, 173/290, BIOCHEMISTRY & MOLECULAR BIOLOGY ).
  21. Yu-Tze Horng, Po-Chi Soo, Bin-Jon Shen, Yu-Li Hung, Kai-Yin Lo, Hsun-Pi Su,Jun-Rong Wei, Shang-Chen Hsieh, Po-Ren Hsueh, Hsin-Chih Lai (2006, Jun). Development of an improved PCR-ICT hybrid assay for direct detection of Legionellae and Legionella pneumophila from cooling tower water specimens.. Water Research., 40(11):2221-2229. (SCI, 1/78, WATER RESOURCES ).
  22. Soo PC, Horng YT, Hsueh PR, Shen BJ, Wang JY, Tu HH, Wei JR, Hsieh SC, Huang CC, Lai HC (2006, Mar). Direct and Simultaneous Identification of Mycobacterium tuberculosis complex (MTBC) and Mycobacterium tuberculosis (MTB) by Rapid Multiplex nested PCR-ICT assay. Journal of Microbiological Methods.. Journal of Microbiological Methods., 66(3):440-448. (SCI, 43/72, BIOCHEMICAL RESEARCH METHODS ).
  23. Jun-Rong Wei, Yu-Huan Tsai, Yu-Tze Horng, Po-Chi Soo, Shang-Chen Hsieh, Po-Ren Hsueh,Jim-Tong Horng, Paul Williams, and Hsin-Chih Lai (2006, Feb). A mobile quorum sensing system in Serratia marcescens.. Bacteriol., 188(4):1518-1525. (SCI, 29/114, MICROBIOLOGY).
  24. Po-Chi Soo, Yu-Tze Horng, Po-Ren Hsueh, Bin-Jon Shen, Jann-Yuan Wang,Hui-Hsin Tu, Jun-Rong Wei, Shang-Chen Hsieh, Chien-Chung Huang,Hsin-Chih Lai (2005, Sep). Characterization of the dapA-nlpB genetic locus involved in regulation of swarming motility, cell envelope architecture, hemolysin production and cell attachment ability in Serratia marcescens.. Immun., 73(9):6075-6084. (SCI, 12/70, INFECTIOUS DISEASES ).
  25. Jun-Rong Wei, Yu-Huan Tsai, Po-Chi Soo, Yu-Tze Horng, Shang-Chen Hsieh,Shen-Wu Ho, and Hsin-Chih Lai (2005, Aug). Biochemical characterization of RssA-RssB, a two-component signal transduction system regulating swarming behavior in Serratia marcescens.. Bacteriol., 187(16):5683-5690. (SCI).
  26. Hsin-Chih Lai, Po-Chi Soo, Jun-Rong Wei, Wen-Ching Yi, Shwu-Jen Liaw,Yu-Tze Horng, Shi-Ming Lin, Shen-Wu Ho, Simon Swift, and Paul Williams (2005, May). The RssAB Two-Component signal transduction system in Serratia marcescens regulates swarming motility and cell envelope architecture in response to exogenous saturated fatty acids.. Bacteriol., 187(10):3407-3414. (SCI).
  27. Yu-Tze Horng,Su-Chen Deng,Mavis Daykin,Po-Chi Soo,Jun-Rong Wei,Kwen-Tay Luh,Shen-Wu Ho,Simon Swift,Hsin-Chih Lai and Paul Williams (2002, Sep). The LuxR family protein SpnR functions as a negative regulator of N-acylhomoserine lactone-dependent quorum sensing in Serratia marcescens.. Microbiol, 45(6):1655-1671. (SCI).
  28. Sunny Ang, Yu-Tze Horng, Jwu-Ching Shu,Wen-Chin Yi, Hsin-Chih Lai, Kwen-Tay Luh,Simon Swift,Po-Chi Soo, Jia-Hurng Liu, Shen-Wu Ho (2001, Mar). The role of RsmA in the regulation of swarming motility in Serratia marcescens.. Biomed. Sci., 8(2):160-169. (SCI).
  29. Liu JH, Lai MJ, Ang S, Shu JC, Soo PC, Horng YT, Yi WC, Lai HC, Luh KT, Ho SW, Swift S (2000, Nov). Role of flhDC in the expression of the nuclease gene nucA, cell division and flagellar synthesis in Serratia marcescens.. Biomed. Sci., 7(6):475-483.. (SCI).
  30. Yi WC, Hsiao S, Liu JH, Soo PC, Horng YT, Tsai WC, Lai HC, Teng LJ, Hsueh PR, Hsieh RF, Luh KT, Ho SW (1998, Sep). Use of fluorescein labelled antibody and fluorescence activated cell sorter for rapid identification of Mycobacterium species.. Biophys. Res. Commun, 250(2):403-408. (SCI)

 

Patents:

  1. A method to produce polyhydroxyvalerate by recombinant Escherichia coli (Application Number：100135702, Application Patent Number：201315809, Issue Date: 2013.04.16)
  2. A method for the polyhydroxybutyrate (PHB) production by using recombinant Escherichia coli (Application number：100103238, Application Patent Number : 201231664, Issue Date: 2012.08.01)
  3. Probe for identification of Mycobacterium tuberculosis and Mycobacterium tuberculosis complex and method using the same (Application number：098122884 Application Patent Number : 201102436, Issue Date : 2011.01.16)
  4. Detecting device (Patent number：M374057, Issue Date : 2010.02.11)