Dr Chang Lua

Dr. Chang Lua

Research background

Organic Synthesis of Sequential polypeptides.

Genetic control of immune responses.

In vitro T cell culture. B cell hybridoma

Immunoassay development

Drugs of abuse assay

 

Special techniques

Long term T cell culture. B cell hybridoma.

Drug of abuse immunoassay and GC/MS confirmation.

 

Research Interests

Analysis of Amphetamine-Type Stimulants Designer Drugs

Employment of GC/MS to analyze compounds of interests.

Collaborative Relationship Expected

LC/MS expertise.

 

Representative Publications

  • LinHR, Lua AC. Detection of acid labile conjugates of ketamine and its metabolities in urine samples collected from pub participants. J Anal Toxicol. 2004;28:181-186.(SCI).
  • Lua AC, Lin HR. A rapid and sensitive ESI-MS screening procedure for ketamine and norketamine in urine samples. J Anal Toxicol. 2004;28:680-684. (SCI)
  • Lin HR, Lua AC. A Fast Screening Procedure for Ketamine and Norketamine in Urine Samples with a Gas Chromatography-Nitrogen Phosphorus Detector. Tzu Chi Medical Journal,17:213-217. 2005. (SCI)
  • Lin HR, Lua AC. A fast GC-MS screening procedure for ketamine and tis metabolites in urine samples. J Food and Drug Anal. 13(2):107-111,2005.(SCI)
  • Lin HR, Lua AC. Simultaneous determination of amphetamines and ketamines in urine by gas chromatography/mass spectrometry. Rapid Commun. Mass Spectrom.20:1724-1730. 2006 (SCI)
  • Ahai C Lua, Yenny Sutono, Tsong-Yung Chou. Enantiomeric quantification of (S)-(+)-methamphetamine in urine by an immunoaffinity column and liquid chromatography–electrospray-mass spectrometry. Analytica Chimica Acta,576:50-5 2006.(SCI)
  • Huei R. Lin, Hsiu L. Lin, Shu F. Lee, Chiareiy Liu, Ahai C. Lua. A fast screening procedure for ketamine and metabolites in urine samples with tandem mass spectrometry. J Anal Toxicol,34:149-154.2010.(SCI)
  • Lin, TC, Lin, DL, Lua, AC. Detection of p-Chloroamphetamine in Urine Samples with Mass Spectrometry.J Anal Toxicol,35:205-210.2011.(SCI)
  • Rohidas S. Sulake, Chinpiao Chen , Huei-Ru Lin, Ahai-Chang Lua. Synthesis of deuterium labeled ketamine metabolite dehydronorketamine-d4. Bioorganic & Medicinal Chemistry Letters 21(19):5719 (2011).(SCI)
  • Lua, IA、Lua, AC*、Lin, SL、Lin, HR. Replacing Immunoassays for Mephedrone, Six Amphetamine Type Stimulants and Ketamines with Flow Injection Analysis Tandem Mass Spectrometry. Journal of Analytical Toxicology,36:575-581 (2012).(SCI)
  • Lin HR, Chen CL, Huang CL, Chen ST, Lua AC. Simultaneous determination of opiates, methadone, buprenorphine and metabolites in human urine by superficially porous liquid chromatography tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2013;925:10-5.(SCI)